Move over H5N1
This makes Bird Flu look like a springtime walk in the meadow.
From
The Guardian:
Bacteria tests reveal how MRSA strain can kill in 24 hours
Scientists have unravelled the workings of a deadly superbug that attacks healthy young people and can kill within 24 hours.
PVL-producing MRSA, a highly-virulent strain of the drug-resistant superbug, methicillin-resistant staphylococcus aureus, has spread around the world and caused deaths in the UK, Europe, the US and Australia. PVL or panton-valentine leukocidin toxin destroys white blood cells and usually causes boils and other skin complaints. But if it infects open wounds it can cause necrotising pneumonia, a disease that rapidly destroys lung tissue and is lethal in 75% of cases.
Thousands of infections have been recorded across the US, but scientists believe the number is likely to rise in Britain.
In 2004 the bug claimed the life of Richard Campbell-Smith, a fit 18-year-old Royal Marine, who died three days after scratching his legs on gorse during a training exercise in Devon. In December an outbreak at Norfolk and Norwich University hospital killed a baby and infected five others. According to the Health Protection Agency there were 106 cases of PVL-MRSA in England and Wales in 2005 and one confirmed death from necrotising pneumonia caused by the infection.
Scientists at the University of Texas in Houston and Lyon University in France conducted experiments into PVL to work out why it was so lethal. They took two batches of normal staphylococcus aureus bacteria and modified one of them to produce the PVL toxin.
The researchers exposed mice to the different groups of bacteria, to see if they developed lung infections. Animals that inhaled the normal staphylococcus were unaffected, but those that inhaled the PVL-producing staphylococcus quickly developed necrotising pneumonia, with some dying within 48 hours. Further tests on the PVL-producing bacteria showed they also produced higher levels of proteins that caused massive inflammation and made the bacteria more "sticky", helping microbes cling to people's skin and making it more easy to spread.
Needs early diagnosis that someone thinking "it's just an infection" might ignore. So far it seems to not be that prevalent but no telling what might happen. We had a recent case of Necrotizing Fascitis in a young boy from the Bellingham area -- he is recovering nicely but will need a lot of plastic surgery before this is all over.
Posted by DaveH at January 19, 2007 10:26 PM