May 27, 2008

An alternative to DEET?

This will be nice -- DEET is nasty stuff and it stings when it gets in your eyes... From WebMD:
Bug Off: Improved Repellents Beat DEET
Compounds Related to Active Ingredient in Peppers May Lead to Longer-Lasting Mosquito Repellents

Imagine dousing yourself with mosquito repellent at the start of summer and remaining bite-free nearly all season long.

Researchers in Gainesville, Fla., have identified several potent mosquito repellents that keep bugs from biting for up to 73 days -- more than three times longer than the current gold standard, N,N-diethyl-m-toluamide, better known as DEET. DEET is the world's most widely used bug repellent.

Alan Katritzky of the University of Florida and colleagues used artificial neural networking software to predict how certain compounds called N-acylpiperidines would keep mosquitoes from feeding on human flesh. N-acylpiperidines are related to the active ingredient in pepper. The researchers identified 23 strong candidates, which they expected to be as effective as DEET.

Two volunteers wore cloth arm patches containing standard amounts of each compound and placed their gloved arms into a cage swarming with 500 mosquitoes. A lot of clock watching ensued. Researchers measured the repellent's duration by simply watching and waiting to see how soon the mosquitoes started feeding on each arm patch worn by the volunteers.

The experiment showed that "most of these novel acylpiperidines were equivalent to or better than DEET in duration of protection," Katritzky writes in the journal article. His team reports that DEET repelled the mosquitoes for 17.5 days. Some of the pepper-based compounds lasted up to 73 days.
Of course, if you take a shower or sweat, the repellent will wash off but still, something this strong and long lasting will present a nice alternative to DEET. I could see impregnated clothing as a vehicle for use. Microcapsules that break and release the chemical. Posted by DaveH at May 27, 2008 12:02 PM
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